The Effect of Porang-Processed Rice (Amorphophallusmuelleri) on LDL and HDL Levels in DM-Diagnosed Patients
Main Article Content
Abstract
Diabetes mellitus (DM) was one of the deadliest diseases in the world. DM was often associated with lipid metabolism error. Porang tubers contain glucomannan which could decrease cholesterol levels. Porang tubers also could be processed into the rice. This study analyzed the effect of porang-processed rice on LDL and HDL levels of DM-diagnosed patients.This study was conducted to determine the effect of porang-processed rice on LDL and HDL levels in DM-diagnosed patients.This study was an experimental study with the Pre-Test and Post-Test Control Group Design method, which used DM-diagnosed patients as research subjects. 24 research subjects were divided into 2 groups: the treatment group was given porang-processed rice and the control group was given white rice for 5 days. Measurement of LDL and HDL levels was carried out in both groups before and after treatment.There was a significant difference in giving porang-processed rice to LDL levels in DM-diagnosed patients (p = 0.021). There was no significant difference in giving porang-processed rice to HDL levels in DM patients (p = 0.102). However, there was a significant differencein deviation between LDL and HDL levelspre-test and post-test (p = 0,002; p = 0,001).There wasa significant difference between LDL levels in DM-diagnosed patients before and after being given porang-processed rice. There was no significant difference between HDL levels in DM patients before and after being given porang-processed rice.
Keyword: Diabetes mellitus, porang tubers, LDL, HDL
Article Details
This work is licensed under a Creative Commons Attribution 4.0 International License.
References
I. World Health Organization. WHO reveals leading causes of death and disability worldwide: 2000-2019 [Internet]. 2020 [cited 2021 Feb 1]. Available from: https://www.who.int/news/item/09-12-2020-who-reveals-leading-causes-of-death-and-disability-worldwide-2000-2019
II. International Diabetes Federation. IDF diabetes atlas. Ed.9 [Internet]. 2019 [cited 2021 Feb 1]. Available from:
https://diabetesatlas.org/en/sections/demographic-and-geographic-outline.html
III. International Diabetes Federation. IDF diabetes atlas. Ed.9 [Internet]. 2019 [cited 2021 Feb 1]. Available from:
https://diabetesatlas.org/en/sections/worldwide-toll-of-diabetes.html
IV. Bertoni AG, Hundley WG, Massing MW, Bonds DE, Burke GL, Goff DC. Heart failure prevalence, incidence, and mortality in the elderly with diabetes. Diabetes Care. 2004;27(3):699–703.
V. Arsana P, Rosandi R, Manaf A, Budhiarta A, Permana H, Sucipta K et al. Panduan pengelolaan dislipidemia di Indonesia 2015. Jakarta: PB. PERKENI; 2015. 1–51 p.
VI. Noviyanti F, Decroli E, Sastri S. Perbedaan kadar LDL-kolesterol pada pasien diabetes melitus tipe 2 dengan dan tanpa hipertensi di RS Dr. M. Djamil Padang tahun 2011. J Kesehat Andalas. 2015;4(2):545–50.
VII. Hoenig M, Sellke F. Insulin resistance is associated with increased cholesterol synthesis, decreased cholesterol absorption and enhanced lipid response to statin therapy. Atherosclerosis. 2010;211(1):260–5.
VIII. Costacou T, Evans R, Orchard T. High density lipoprotein cholesterol in diabetes: is higher always better? J Clin Lipidol. 2011;5(5):387–94.
IX. Schofield JD, Liu Y, Rao-Balakrishna P, Malik RA, Soran H. Diabetes dyslipidemia. Diabetes Ther. 2016;7(2):203–19.
X. Yanuriati A, Marseno DW, Rochmadi, Harmayani E. Characteristics of glucomannan isolated from fresh tuber of Porang (Amorphophallus muelleri Blume). Carbohydr Polym. 2017;156:56–63.
XI. Pasaribu G, Waluyo TK, Pari G, Hastuti N. The effectiveness of glucomannan and nano activated-carbon as hypercholesterol-lowering agents. Indones J For Res. 2020;7(2):155–64.
XII. Chua M, Baldwin TC, Hocking TJ, Chan K. Traditional uses and potential health benefits of Amorphophallus konjac K. Koch ex N.E.Br. J Ethnopharmacol. 2010;128(2):268–78.
XIII. González-Torres L, Matos C, Vázquez-Velasco M, Santos-López JA, Sánchez-Martínez I, García-Fernández C, et al. Glucomannan- and glucomannan plus spirulina-enriched pork affect liver fatty acid profile, LDL receptor expression and antioxidant status in Zucker fa/fa rats fed atherogenic diets. Food Nutr Res. 2016;61(1):1–14.
XIV. Chen HL, Chen YC, Liaw YP, Sheu WHH, Tai TS. Konjac supplement alleviated hypercholesterolemia and hyperglycemia in type 2 diabetic subjects. J Am Coll Nutr. 2003;22(1):36–42.
XV. Alamsyah M. Pengaruh glukomanan terhadap penurunan risiko penyakit stroke iskemik. J Ilm Kesehat Sandi Husada. 2019;10(2):292–8.
XVI. Susanti N. Suplementasi tepung porang (Amorphophallus muelleri Blume) sebagai nutraceutical dalam manajemen diabetes melitus tipe 2. El-Hayah. 2014;5(1):9–16.
XVII. Fairudz A. Pengaruh serat pangan terhadap kadar kolesterol penderita overweight. J Major. 2015;4(8):121–6.
XVIII. Urli TI, Hariyanto T, Novita D. Pengaruh pemberian tepung porang (Amorphophallus muelleri Blume) terhadap kadar HDL pada tikus (Rattus novergicus) strain wistar DM tipe 2. Bioconjug Chem. 2017;2(2):652–64.
XIX. American Diabetes Association. Nutrition recommendations and interventions for diabetes: A position statement of the American Diabetes Association. Diabetes Care. 2008;31(SUPPL. 1).