https://ijpbms.com/index.php/ijpbms/issue/feedInternational Journal of Pharmaceutical and Bio Medical Science2025-04-05T15:11:53+00:00Open Journal Systems<p>International Journal Of Pharmaceutical And Bio Medical Science is a leading international journal for publication of new ideas.The primary goal of the editors is to maintain high quality of publications on theoretical developments and practical applications. Original research papers, state-of-the-art reviews, and high quality technical notes are invited for publications. Authors should note that only original and previously unpublished manuscripts will be considered. The articles that are sent for reviews will have names of the authors deleted with a view towards enhancing the objectivity and fairness of the review process. Time to time, the Journal will publish review articles and bring out special issues on a specific field. Authors are encouraged to contact the Editors if they would like to submit a review article or bring out a special issue of the Journal. Submission of a manuscript is interpreted as a statement of certification that no part of the manuscript is copyrighted by any other publication nor is under review by any other formal publication. It is the primary responsibility of the author to obtain proper permission for the use of any copyrighted materials in the manuscript, prior to the submission of the manuscript to <strong>IJPBMS.</strong></p> <p> </p> <p><strong>Submission Open for April Edition-2021</strong></p> <p>Last Date of Article Submission: 25 September</p> <p>Acceptance Notification: within a week</p> <p>Submission Id: editor@ijpbms.com</p>https://ijpbms.com/index.php/ijpbms/article/view/721Prevalence of Gingivitis and Dental Caries in Early Childhood: A Cross-Sectional Study at TK Tat Twam Asi, Pesanggrahan, South Jakarta2025-03-27T14:05:15+00:00Annisa Soxyasfuridah31@gmail.comNisrina A. Putrioxyasfuridah31@gmail.comNur Koxyasfuridah31@gmail.comNurul I. Somadinataoxyasfuridah31@gmail.comOldilia Yoxyasfuridah31@gmail.comOriza Soxyasfuridah31@gmail.comOxy Ansorioxyasfuridah31@gmail.comPuja S.H. Latuponooxyasfuridah31@gmail.comPutri Noxyasfuridah31@gmail.com<p><strong>Introduction:</strong> Oral health is an integral part of overall health, yet it is often neglected in global and national policies. Periodontal diseases such as gingivitis and dental caries are major issues in children that can affect their quality of life. This study was conducted to identify the prevalence of periodontal disease and dental caries among children at TK Tat Twam Asi, Pesanggrahan, South Jakarta.</p> <p><strong>Objective:</strong> This study aims to evaluate the oral health status and dental care habits of children. Method: The research employed a cross-sectional design with random sampling techniques. The sample consisted of 36 children aged 3–6 years. Data were collected through dental examinations and parent/guardian questionnaires. Analysis was performed using SPSS version 24.</p> <p><strong>Conclusion:</strong> The study found that 97.2% of children had gingivitis, and 86.1% had dental caries. Key risk factors included poor brushing habits, frequent consumption of sugary foods, and low use of fluoride toothpaste. This study highlights the importance of educating parents about oral hygiene, promoting healthy eating habits, and improving access to preventive dental care to reduce the prevalence of oral diseases in children.</p>2025-04-05T00:00:00+00:00Copyright (c) 2025 International Journal of Pharmaceutical and Bio Medical Sciencehttps://ijpbms.com/index.php/ijpbms/article/view/715Antibacterial Activity of Kitolod (Isotoma Longiflora L.) Herb Extract and Fractions Against the Growth of Dental Carises Causing Bacteria Streptococcus Mutans2025-03-19T02:29:24+00:00Oktafianti A. Nurafifahandinivia144@gmail.comDaniel Lantangdaniel.lantang@fmipa.uncen.ac.idRani Dewi Pratiwiranidp2987@gmail.comKrisna Dewikrisnadewi001@gmail.comNUR FADILAH BAKRInfadhilah88@gmail.com<p>The Kitolod herb (<em>Isotoma longiflora </em>L.) has empirically been used to treat several diseases. Kitolod herb contains some secondary metabolite compounds, such as flavonoids, tannins, and saponins, which are antibacterial. This study aims to determine the inhibition of antibacterial activity and the most effective concentration in inhibiting <em>Streptococcus mutans</em> bacteria. The sample used in this study was Kitolod herb obtained from Sentani Regency. Then, the sample was extracted using the maceration method with 96% ethanol solvent. Then, it was fractionated using the solvent of ethanol-water, ethyl-acetate, and n-hexane. The antibacterial activity testing used the disc diffusion method. This study used a completely randomized design with nine treatments that included the concentrations of 50 ppm, 100 ppm, 200 ppm, 400 ppm, 600 ppm, 800 ppm, 1000 ppm, amoxicillin (positive control), sterile distilled water (negative control). The results showed that the extract of Kitolod herb has activity as an antibacterial on <em>Streptococcus mutans </em>at the highest concentration of 1000 ppm of 10.20 mm (strong category). The testing results on the three fractions showed that the ethyl-acetate fraction has the most significant inhibition activity of 8,16 mm at a concentration of 1000 ppm (medium category). The result showed that the extract and fraction of Kitolod herb (<em>Isotoma longiflora </em>L.) have the potential to be an antibacterial to inhibit <em>Streptococcus mutans</em> bacteria.</p>2025-04-14T00:00:00+00:00Copyright (c) 2025 International Journal of Pharmaceutical and Bio Medical Science