Interaction Analysis of Smoking with Liver Function Tests

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Published: Nov 12, 2022
DOI: https://doi.org/10.47191/ijpbms/v2-i11-07
Keywords:
cigarette smoking, water-pipe smoking, liver enzymes, ALT, AST, LDH

Main Article Content

Ahlam Mohammed Alqaseer
Ministry of Health, Saudi Arabia
Ibrahim Zaid Ibrahim Almgli
Ministry of Health, Saudi Arabia
Ghadah Ahmad Alfaqeeh
Ministry of Health, Saudi Arabia
Hassan Abdullah Alshehri
Ministry of Health, Saudi Arabia
Abdulaziz Sultan Suliman Alsultan
Ministry of Health, Saudi Arabia
Nader Sager Almotriy
Ministry of Health, Saudi Arabia
Mohammed Zamel M Alsubaie
Ministry of Health, Saudi Arabia
Falah Sameer Alharbi
Ministry of Health, Saudi Arabia
Naif Hassan ALmazrou
Ministry of Health, Saudi Arabia

Abstract

Introduction: Smoking has been linked to harmful health impacts on several body organs including the cardiovascular system.


Study objectives: The primary goal of the current study is to assess how smoking models affect the level of liver enzymes.


Methods: Thirty male albino rats served as the subjects for this experimental study. We used male albino rats (Rattusratas) that were 6–8 weeks old and weighed 50–180 g. Rats were randomly allocated to one of three groups (n = 10): group 1 served as a negative control and was solely exposed to fresh air; group 2 was exposed to the most popular cigarette brands available in Jordan (red LM cigarettes) at a rate of 1 cigarette per rat per day for 30 days. Rats in group 3 were given flavored water pipes for 30 days, once a day for the entire body, after completely burning 20 g of one moassal. The smoking device was digital. LDH, AST, ALT, and liver enzymes were assessed in study groups. The collected data were examined using SPSS version 20.


Results: Both exposures to cigarette smoking and water pipe smoking resulted in a considerable rise in liver enzymes. Interesting results showed that quitting smoking restored liver enzymes to levels close to those of the control group.


Conclusion: Increased levels of liver enzymes are a sign that smoking causes liver damage, which can be reversed by quitting.

Article Details

How to Cite
Mohammed Alqaseer, A. ., Ibrahim Almgli, I. Z. ., Ahmad Alfaqeeh, G. ., Abdullah Alshehri, H. ., Suliman Alsultan, A. S. ., Almotriy, N. S. ., Zamel M Alsubaie, M., Alharbi, F. S., & ALmazrou, N. H. . (2022). Interaction Analysis of Smoking with Liver Function Tests. International Journal of Pharmaceutical and Bio Medical Science, 2(11), 513–517. https://doi.org/10.47191/ijpbms/v2-i11-07
Issue
Vol. 2 No. 11 (2022): Volume 02 Issue 11 November 2022
Section
Articles
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This work is licensed under a Creative Commons Attribution 4.0 International License.

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