The Effectiveness of Bajakah Wood Extract (Spatholobus Littoralis Hassk) From South Kalimantan against Candida Albicans ATCC 10231

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Published: Dec 12, 2024
DOI: https://doi.org/10.47191/ijpbms/v4-i12-05
Keywords:
Bajakah wood, Candida albicans, Root Canal Treatment

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Rina Permatasari
Dental Conservation Department Prof. Dr. Moestopo (B) University, Pesanggrahan, Jakarta 12330, Indonesia
Mutiara Azhar Riyanto
Faculty of Dentistry Prof. Dr. Moestopo (B) University, Pesnaggrahan, Jakarta 12330, Indonesia

Abstract

Root canal treatment (RCT) is a procedure performed to remove inflamed or infected pulp tissue. Candida albicans is the most pathogenic type of fungus found in the oral cavity, accounting for 80%. Bajakah wood (Spatholobus littoralis Hassk) contains antifungal components such as phenols, flavonoids, tannins, and saponins. This research is to determine the antifungal effectiveness of Bajakah wood (Spatholobus littoralis Hassk) against Candida albicans. This research is an experimental laboratory study using the dilution method in the laboratory. A total of 20 samples of Candida albicans ATCC 10231 cultures in Sabouraud Dextrose Broth medium were tested. The treatment variations of Bajakah wood were concentrations of 50%, 75%, 100%, and 2.5% NaOCl (K+) with 5 repetitions. The results showed that the average number of fungal growths at 50% concentration was 387, at 75% concentration it was 449.4, while at 100% concentration it was 2.4, and in the positive control it was 1. Data analysis using the Kruskal-Wallistest showed significant differences (p<0.05) across all treatment groups. It can be concluded that Bajakah wood at 100% concentration has the highest antifungal content and is effective in inhibiting the growth of Candida albicans.

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How to Cite
Rina Permatasari, & Riyanto, M. A. (2024). The Effectiveness of Bajakah Wood Extract (Spatholobus Littoralis Hassk) From South Kalimantan against Candida Albicans ATCC 10231. International Journal of Pharmaceutical and Bio Medical Science, 4(12), 946–948. https://doi.org/10.47191/ijpbms/v4-i12-05
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Vol. 4 No. 12 (2024): Volume 04 Issue 12 December 2024
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Articles
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This work is licensed under a Creative Commons Attribution 4.0 International License.

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