Precision Medicine in Pediatric Oncology- Is it the Way Forward?
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Abstract
Precision medicine is currently an emerging approach for the treatment of childhood cancer. The use of improved molecular diagnostic techniques has facilitated the identification of actionable molecular targets and hence additional therapeutic opportunities. Next generation sequencing (NGS) has revolutionized our understanding of pediatric cancer and fueled the personalized approach to cancer treatment. Treatment of patients with pediatric cancer is not synonymous with treatment in a mini adult. Pediatric cancers have different genetic constitution and fewer molecular targets as compared to adult tumors. This overview discusses the diagnostic and therapeutic advancements along with some of the important clinical implications and the future prospects of precision medicine in pediatric oncology.
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