A Systemic Review of Organophosphorus Poisoning by Analyzing the Case Report

Abstract

Introduction: Poison is any substance that obstructs with ordinary body functions and is capable of affecting adverse effects in living organisms. Self-poisoning from organophosphorus [OP] pesticides is a significant clinical issue in rural areas of developing countries and is responsible for an estimated 2,00,000 fatalities annually. Suspicion recognizable clinical symptoms the odour of pesticides or solvents and decreased butyrylcholinesterase activity in the blood are used for diagnosis.

Case Study: A 30 years old female patient was admitted in a Tertiary Care Hospital, with an alleged history of dimethoate compound poisoning. On arrival the patient was drowsy responds to painful stimuli and afebrile. The treatment was begin with Gastric lavage with normal saline Inj.Pralidoxime in an intravenous route and Atropine was also administered intravenously and repeated every 5 minutes until the pupil dilated and Ranitidine was given to prevent ulceration.

Discussion: The initial method to treat organophosphorus poisoning is to decontaminate the patient by removing and destroying all clothing and using drying agent such as flour sand or bentonite. The patient's irrational usage of medication therapy causes a worsening of the condition and a 10- to 15-day hospitalization.

Conclusion: As per the standard treatment guidelines, atropine should be given as first-line therapy because muscarinic effects are reversed by atropine. By providing this to the patient, you will minimise the severity of their illness minimise down on their stay in the hospital and ultimately save their lives.