Effect of Phenolic Extract of Cress Seed on Cations and Osmolality in Rabbit Seminal Plasma

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Shaymaa Abd Al-jasim Al shukri

Abstract

This study aimed to investigated the effect of cress seeds phenolic extract as an antioxidant on cations and osmolality of rabbit seminal plasma. Four groups (24 male and 10 female) of rabbits were taken (N=6). First group was control (Distilled water) and other groups received orally phenol extract (30, 60 and 90 mg/kg), once daily for 60 days. The information of cations concentrations and osmolality of seminal plasma were collected and evaluated. The concentrations of copper, cadmium, lead and potassium were significantly declined (p0.05). While the concentration of iron, sodium, calcium and osmolality increased significantly in the seminal plasma of experimental groups compared to control. Through the results, the appropriate dose of phenolic extract from local plant Rashad can be used as a medicine in improving human fertility through its role in reducing the damage of trace elements and improving semen osmolality, and as results of its antioxidant function.

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How to Cite
Shaymaa Abd Al-jasim Al shukri. (2023). Effect of Phenolic Extract of Cress Seed on Cations and Osmolality in Rabbit Seminal Plasma. International Journal of Pharmaceutical and Bio Medical Science, 3(8), 410–416. https://doi.org/10.47191/ijpbms/v3-i8-05
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References

I. Alalwany, E.A., Altaee,N.S.N., Al-Khamas,AJ.H. & Rashid ,K.H.(2021). Histological changes in the testes, epididymis and seminal vesicles of adult male rabbits treated with garden cress (Lepidium sativum L.) seeds phenolic extract. Biochem. Cell. Arch. 21, 2079-2083.

II. Motlagh, M.K., Sharafi, M., Zhandi, M., Mohammadi-Sangcheshmeh, A., Shakeri, M.,Soleimani, M. & Zeinoaldini, S. (2014). Antioxidant effect of rosemary (Rosmarinusofficinalis L.) extract in soybean lecithin-based semen extender following freeze–thawing process of ram sperm. Cryobiology. 69, 217-222.

III. Aydemir, T.&Becerik ,S. (2011). Phenolic content and antioxidant activity of different extracts from ocimum basilicum, apium graveolens and lepidium sativum seeds. journal of food biochemistry ;35 (1): 62-79.

IV. Russell, L. D., Ren, H. P.,Sinha Hikim, I., Schulze, W., & Sinha Hikim, A. P. (1990). Acomparative study in twelve mammalian species of volume densities, volumes, and numerical densities of selected testis components, emphasizing those related to the Sertoli cell. Am. J. Anat.vol. 188, 1990, no. 1, p. 21-30.

V. Stegmayer, B. & Ronquist, G. (1982). Stimulation of Sperm progressive, motility by organelles in human seminal plasma. Scand. J. Urol. Nephrol., 16:85- 94.

VI. Kalita, D.J., Sarmah, B.C. & Goswami,S. (2006). Effect of mineral supplementation on seminal plasma of Assam local goat. Indian Journal of Applied Animal Research, 40(1):162-165.

VII. Hamamah,S. & Gatti,G. (1998). Role of the ionic environment and internal pH on sperm activity.Human Reproduction, Volume 13, Issue suppl_4, 1 December 1998, Pages 20–30, .

VIII. Cevik, M., Tuncer, P.B., Tasdemir, U. & Özgürtas, T. (2007). Comparison of

IX. spermatological characteristics and biochemical seminal plasma parameters of Normo-zoospermic and Oligoastheno-zoospermic Bulls of Two Breeds. Turkish Journal of Veterinary & Animal Sciences, 31(6):381-387.

X. Eskenazi, B., Kidd, S.A., Marks, A.R., Sloter, E., Block ,G. & Wyrobek, A.J.(2005). Antioxidant intake is associated with semen quality in healthy men. Hum Reprod 2005; 20: 1006-1012.

XI. Shahidi, F., Janitha, P.K. &Wanasundara, P.(1992). Phenolic antioxidants. Crit Rev Food Sci 1992; 32: 67-102.

XII. Nayak , P. S., Upadhyaya , S. D. &Upadhyaya , A. (2009). A HPTLC densitometer determination of sinapic acid in Chandrasur (Lepidium sativum). J. Sci. Res. ;1 (1): 121-127.

XIII. Ferramosca, A. & Zara, V.(2022). Diet and Male Fertility: The Impact of Nutrients and Antioxidants on Sperm Energetic Metabolism. Int. J. Mol. Sci. 2022, 23, 2542.

XIV. Maury,G.L., Rodríguez,D.M., Hendrix ,S. et al. (2020). “Antioxidants in plants: A valorization potential emphasizing the need for the conservation of plant biodiversity in Cuba,” Antioxidants, vol. 9, no. 11, p. 1048, 2020.

XV. Frei, B.(1995). Cardiovascular disease and nutrient antioxidants: role of low-density lipoprotein oxidation. Crit Rev Food Sci Nutr 1995; 35: 83-98.

XVI. Rio, D.D., Rodriguez-Mateos, A., Spencer, J.P.E., Tognolini,M., Borges,G. & Crozier A.(2013). Dietary (poly)phenolics in human health: structures, bioavailability, and evidence of protective effects against chronic diseases. Antioxid Redox Signal 2013; 18(14): 1818-1892.

XVII. Doke ,S. & Guha,M.(2015). Identification of Extraction Conditions for Determination of Phenolic Contents of Garden Cress Seed (Lepidium sativum L.) and Its Milled Fractions. Food Analytical Methods. April 2015, Volume 8, Issue 4, pp 1053–1057.

XVIII. Ardeshirnia,R., Zandi,M. & Sanjabi,M.R. (2017). The effect of quercetin on fertility of frozen-thawed ram epididymal spermatozoa. South African Journal of Animal Science 2017, 47 (No. 2). 237-244.

XIX. Malara,J., Chairmanb,K., Singhc,A.R.J., Vanmathid,J.S., Balasubramaniana,A. & Vasanthie,K. (2014). Antioxidative activity of different parts of the plant Lepidium sativum Linn. Biotechnology Reports3(2014)95–98.

XX. Naji.N.S. & Abood,F.N. (2013).Changes in Sperm Parameters of Adult Male Rabbits by Phenol Extract of Lepidium Sativum Seeds. Journal of Natural Sciences Research www.iiste.org.Vol.3, No.8, 2013.17-22.

XXI. Sakhaee,E. Emadi ,L. & Siahkouhi,H. (2016). Histopathological evaluation of supportive effects of Rosa damascene on mice testes, following long term administration of copper sulfate. Asian Pacific Journal of Reproduction 2016; 5(1): 46–50.

XXII. Babaei ,H. & Abshenas, J. (2013). Zinc therapy improves adverse effects of long term administration of copper on epididymal sperm quality of rats. Iran J Reprod Med 2013; 11: 577-582.

XXIII. Al-Taee.,N.S.N.(2005).Effect of Cadmium In Fertility of The Native Rabbits. A Thesis, University of Babylon, Iraq.

XXIV. Pires, V.C., Gollu¨cke,A.P.B., Ribeiro,D.A., Lungato,L., Almeida,V. & Aguiar,O. Jr.(2013). Grape juice concentrate protects reproductive parameters of male rats against cadmium-induced damage: a chronic assay. British Journal of Nutrition (2013), 110, 2020–2029 .

XXV. Bhattacharjee, A., Kulkarni,V.H., Habbu,BV. & Chakraborty,M. (2018). Detrimental effects of lead on human health and protective effect by natural polyphenols: a review. international research journal of pharmacy. review article: Int. Res. J. Pharm. 2018, 9 (6):4-13.

XXVI. Hussain,S.A. & Jaccob,A.A. (2013).“Effects of Single Oral Doses of Flavonoids on Absorption and Tissue Distribution of Orally Administered Doses of Trace Elements in Rats.” American Journal of Pharmacological Sciences 1, no. 5 (2013): 84-89.

XXVII. Morisawa,M., Suzuki,K. & Morisawa,S. (1983). Effects of potassium and osmolality on spermatozoan motility of salmonid fishes.J. exp. Biol. 107, 105-113 (1983) 105.

XXVIII. Ambali A. L., Anoh K. U. & Suleiman I. O. (2018). Relationships between sperm morphology and semen cation concentrations in red sokoto goats (Capra aegagrus hircus). International Journal of Livestock Production. Vol. 9(6), pp. 108-111, June 2018.

XXIX. Zamiri, M.J. & Khodaei ,H.R. (2005). Seasonal thyroidal activity and reproductive characteristics of Iranian fat-tailed rams. Animal Reproduction Science, 88(3-4):245-255.

XXX. Akpa, G.N., Ambali ,A.L. & Suleiman ,I.O. (2013). Relationships between semen cation concentrations, semen characteristics, testicular measurements and body conformation traits in Red Sokoto Goat.Natural Sciences, 11(7):94-99.

XXXI. Silva, E.C.B., Cajueiro, J.F.P., Silva, S.V., Soares, P.C. & Guerra, M.M.P. (2012). Effect of antioxidants resveratrol and quercetin on in vitro evaluation of frozen ram sperm. Theriogenology. 77, 1722-1726.

XXXII. White, I. G. (1962). Physiology of mammalian sperm. In: Reproduction in Farm Animals, pp. 57-78. Ed. E. S. E. Hafez. Lea & Febiger, Philadelphia.

XXXIII. Mann, T. (1964). The biochemistry of semen and of the male reproductive tract. Methuen, London.

XXXIV. Chang, M. C. & Thorsteinsson, T. (1958). Effects of osmotic pressure and hydrogen-ion concentration on the motility and fertilizing capacity of rabbit spermatozoa. Fert. Steril. 9, 510.