PJM and Cryotherapy in a New Approach for Spasticity Management: An Experimental Trial

Main Article Content

Farhat Zahraa
Khalaf Fatima
Fakih Ali
Ashour Amal
Haidar Hassan Khodor
Kheireddine Hassane

Abstract

Background: Spasticity has been proven to affect the quality of life and functional rehabilitation in patients post-stroke. Several studies aimed to investigate ways to reduce muscle tonicity in this population.  Peripheral joint mobilization (PJM) as well as cryotherapy can be used effectively to reduce spasticity and enhance the range of motion.


Objectives: This study aimed to investigate the direct effect of cryotherapy, and that of peripheral joint mobilization, on spasticity as a primary outcome and range of motion as a secondary outcome in stroke patients.


Methods: Eighteen participants met the inclusion criteria. Patients with ankle plantarflexor spasticity (n=14), patients with biceps brachii spasticity (n=13), and patients with triceps brachii spasticity (n=10) underwent our interventions on two distinct visits. On the first session, Kaltenborn’s PJM was performed, while on the second session ice-massaging technique was applied on the biceps brachii, triceps brachii, and gastrocnemius muscles over the duration of five continuous minutes. The assessment tools used were Modified ashworth scale (MAS) to assess spasticity level and goniometer to evaluate the range of motion (ROM). Statistical tests were performed using SPSS software, Version 23.0.


Results: Cryotherapy and peripheral joint mobilization showed a significant reduction in spasticity of the biceps brachii and triceps brachii muscles (p < 0.05), while only cryotherapy had a significant change on gastrocnemius muscle. For ROM, only PJM showed a significant positive change on both active and passive ranges.


Conclusion: Both modalities showed effectiveness in direct reduction of spasticity, hence contributing to a more manageable and practical functional rehabilitation of stroke patients

Article Details

How to Cite
Zahraa, F. ., Fatima, K. ., Ali, F. ., Amal, A., Khodor, H. H., & Hassane, K. . (2022). PJM and Cryotherapy in a New Approach for Spasticity Management: An Experimental Trial. International Journal of Pharmaceutical and Bio Medical Science, 2(08), 302–313. https://doi.org/10.47191/ijpbms/v2-i8-07
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References

I. Alcantara, C. C., Blanco, J., De Oliveira, L. M., Ribeiro, P., Herrera, E., Nakagawa, T. H., Reisman, D. S., Michaelsen, S. M., Garcia, L. C., & Russo, T. L. (2019). Cryotherapy reduces muscle hypertonia, but does not affect lower limb strength or gait kinematics post-stroke: a randomized controlled crossover study. Topics in stroke rehabilitation, 26(4), 267–280.

II. An, C. M., & Jo, S. O. (2017). Effects of Talocrural Mobilization with Movement on Ankle Strength, Mobility, and Weight-Bearing Ability in Hemiplegic Patients with Chronic Stroke: A Randomized Controlled Trial. Journal of stroke and cerebrovascular diseases: the official journal of National Stroke Association, 26(1), 169–176.

III. An, C. M., & Jo, S. O. (2017). Effects of Talocrural Mobilization with Movement on Ankle Strength, Mobility, and Weight-Bearing Ability in Hemiplegic Patients with Chronic Stroke: A Randomized Controlled Trial. Journal of stroke and cerebrovascular diseases: the official journal of National Stroke Association, 26(1), 169–176.

IV. An, C. M., & Won, J. I. (2016). Effects of ankle joint mobilization with movement and weight-bearing exercise on knee strength, ankle range of motion, and gait velocity in patients with stroke: a pilot study. Journal of physical therapy science, 28(2), 689–694.

V. An, C. M., & Won, J. I. (2016). Effects of ankle joint mobilization with movement and weight-bearing exercise on knee strength, ankle range of motion, and gait velocity in patients with stroke: a pilot study. Journal of physical therapy science, 28(2), 689–694.

VI. Bagg, S., Pombo, A. P., & Hopman, W. (2002). Effect of age on functional outcomes after stroke rehabilitation. Stroke, 33(1), 179–185.

VII. Balci B. P. (2018). Spasticity Measurement. Noro psikiyatri arsivi, 55(Suppl 1), S49–S53.

VIII. Bassett, S. W., & Lake, B. M. (1958). Use of Cold Applications in the Management of Spasticity. Physical Therapy, 38(5), 333–334.

IX. Bell, K. R., & Lehmann, J. F. (1987). Effect of cooling on H- and T-reflexes in normal subjects. Archives of physical medicine and rehabilitation, 68(8), 490–493.

X. Bethoux, F. (2015). Spasticity Management After Stroke. Physical Medicine and Rehabilitation Clinics of North America, 26(4), 625–639.

XI. Boyd, R. N., & Ada, L. (n.d.). Physiotherapy management of spasticity. Upper Motor Neurone Syndrome and Spasticity, 79–98.

XII. Cheung, J., Rancourt, A., Di Poce, S., Levine, A., Hoang, J., Ismail, F., Boulias, C., & Phadke, C. P. (2015). Patient-identified factors that influence spasticity in people with stroke and multiple sclerosis receiving botulinum toxin injection treatments. Physiotherapy Canada. Physiotherapie Canada, 67(2), 157–166.

XIII. Cho, K. H., & Park, S. J. (2020). Effects of joint mobilization and stretching on the range of motion for ankle joint and spatiotemporal gait variables in stroke patients. Journal of stroke and cerebrovascular diseases: the official journal of National Stroke Association, 29(8), 104933.

XIV. Cho, K. H., & Park, S. J. (2020). Effects of joint mobilization and stretching on the range of motion for ankle joint and spatiotemporal gait variables in stroke patients. Journal of stroke and cerebrovascular diseases: the official journal of National Stroke Association, 29(8), 104933.

XV. Darade, S. (2015). Can icing is help to reduce Spasticity, improving ankle range of motion and gait velocity in post stroke subjects.

XVI. Denton, A., Bunn, L., Hough, A., Bugmann, G., & Marsden, J. (2016). Superficial warming and cooling of the leg affects walking speed and neuromuscular impairments in people with spastic paraparesis. Annals of physical and rehabilitation medicine, 59(5-6), 326–332.

XVII. Elanchezhian, Ch, Swarnakumari, P. Efficacy of Cold Therapy and Passive Stretching to Improve Gait in Spastic Diplegic Cerebral Palsy Children. Int J Pediatr 2019; 7(9): 10109-118.

XVIII. El-Hajj, M., Salameh, P., Rachidi, S., & Hosseini, H. (2016). The epidemiology of stroke in the Middle East. European Stroke Journal, 1(3), 180–198.

XIX. El-Maksoud, G., Sharaf, M.A., & Rezk-Allah, S.S. (2011). Efficacy of cold therapy on spasticity and hand function in children with cerebral palsy. Journal of Advanced Research, 2, 319-325.

XX. El-Maksoud, G., Sharaf, M.A., & Rezk-Allah, S.S. (2011). Efficacy of cold therapy on spasticity and hand function in children with cerebral palsy. Journal of Advanced Research, 2, 319-325.

XXI. Felice, T. D., & Santana, L. R. (2009). Recursos Fisioterapêuticos (Crioterapia e Termoterapia) na espasticidade: revisão de literatura. Revista Neurociências, 17(1), 57–62.

XXII. Fink, J. N., Frampton, C. M., Lyden, P., Lees, K. R., & Virtual International Stroke Trials Archive Investigators (2008). Does hemispheric lateralization influence functional and cardiovascular outcomes after stroke?: an analysis of placebo-treated patients from prospective acute stroke trials. Stroke, 39(12), 3335–3340.

XXIII. Fink, J. N., Frampton, C. M., Lyden, P., Lees, K. R., & Virtual International Stroke Trials Archive Investigators (2008). Does hemispheric lateralization influence functional and cardiovascular outcomes after stroke?: an analysis of placebo-treated patients from prospective acute stroke trials. Stroke, 39(12), 3335–3340.

XXIV. Garcia, L. C., Alcântara, C. C., Santos, G. L., Monção, J. V. A., & Russo, T. L. (2018). Cryotherapy reduces muscle spasticity but does not affect proprioception in ischemic stroke. American Journal of Physical Medicine & Rehabilitation.

XXV. Ghai, A., Garg, N., Hooda, S., & Gupta, T. (2013). Spasticity - Pathogenesis, prevention and treatment strategies. Saudi journal of anaesthesia, 7(4), 453–460.

XXVI. Global Health Estimates: Life expectancy and leading causes of death and disability. (2019). World Health Organization. https://www.who.int/data/gho/data/themes/mortality-and-global-health-estimates

XXVII. Guimarães, S. S. F., Coelho, C. de F., & Carruba, L. B. (2014). Effects of cryotherapy on tonic adequacy upper limb hemiparesis after stroke. Manual Therapy, Posturology & Rehabilitation Journal, 1-9.

XXVIII. Hankey, G. J., Jamrozik, K., Broadhurst, R. J., Forbes, S., & Anderson, C. S. (2002). Long-Term Disability After First-Ever Stroke and Related Prognostic Factors in the Perth Community Stroke Study, 1989-1990. Stroke, 33(4), 1034–1040.

XXIX. Harris, J. E., & Eng, J. J. (2006). Individuals with the dominant hand affected following stroke demonstrate less impairment than those with the nondominant hand affected. Neurorehabilitation and neural repair, 20(3), 380–389

XXX. Hegedus, E. J., Goode, A., Butler, R. J., & Slaven, E. (2011). The neurophysiological effects of a single session of spinal joint mobilization: does the effect last?. The Journal of manual & manipulative therapy, 19(3), 143–151.

XXXI. Herrera, E., Sandoval, M. C., Camargo, D. M., & Salvini, T. F. (2010). Motor and sensory nerve conduction are affected differently by ice pack, ice massage, and cold water immersion. Physical therapy, 90(4), 581–591.

XXXII. Kachmar, O., Kushnir, A., Matiushenko, O., & Hasiuk, M. (2018). Influence of Spinal Manipulation on Muscle Spasticity and Manual Dexterity in Participants With Cerebral Palsy: Randomized Controlled Trial. Journal of chiropractic medicine, 17(3), 141–150.

XXXIII. Kachmar, O., Kushnir, A., Matiushenko, O., & Hasiuk, M. (2018). Influence of Spinal Manipulation on Muscle Spasticity and Manual Dexterity in Participants With Cerebral Palsy: Randomized Controlled Trial. Journal of chiropractic medicine, 17(3), 141–150

XXXIV. Kachmar, O., Voloshyn, T., & Hordiyevych, M. (2016). Changes in Muscle Spasticity in Patients with Cerebral Palsy After Spinal Manipulation: Case Series. Journal of chiropractic medicine, 15(4), 299–304.

XXXV. Kaltenborn FM, Kaltenborg FM, Kaltenborn TB, Vollowitz E, Evjenth O, Morgan D. Manual Mobilization of the Joints: The Kaltenborn Method of Joint Examination and Treatment: Traction-Manipulation of the Extremities and Spine. Oslo: Norli; 2008

XXXVI. Khandare, S., & Palekar, T. (2012). Comparison of post 24 hours effect of cooling and sustained passive stretching as treatment techniques for reduction of spasticity in hemiplegics using h-reflex -. International journal of current research and review, 4, 144-148.

XXXVII. Kim, Y.-H., Jang, H.-J., & Kim, S.-Y. (2014). Effect of Hip Joint Mobilization on Hip Mobility, Balance and Gait With Stroke Patients. Physical Therapy Korea, 21(2), 8–17.

XXXVIII. Knutsson E. (1970). Topical cryotherapy in spasticity. Scandinavian journal of rehabilitation medicine, 2(4), 159–163.

XXXIX. Krukowska, J., Dalewski, M., & Czernicki, J. (2014). Ocena skuteczności krioterapii miejscowej u osób ze spastycznością po udarze mózgu [Evaluation of effectiveness of local cryotherapy in patients with post-stroke spasticity]. Wiadomosci lekarskie (Warsaw, Poland: 1960), 67(2 Pt 1), 71–75.

XL. Kuo, C.-L., & Hu, G.-C. (2018). Post-stroke Spasticity: A Review of Epidemiology, Pathophysiology, and Treatments. International Journal of Gerontology.

XLI. Lee, S. U., Bang, M. S., & Han, T. R. (2002). Effect of cold air therapy in relieving spasticity: applied to spinalized rabbits. Spinal cord, 40(4), 167–173.

XLII. Lundström, E., Smits, A., Terént, A., & Borg, J. (2010). Time-course and determinants of spasticity during the first six months following first-ever stroke. Journal of Rehabilitation Medicine, 42(4), 296–301.

XLIII. Macciocchi, S. N., Diamond, P. T., Alves, W. M., & Mertz, T. (1998). Ischemic stroke: relation of age, lesion location, and initial neurologic deficit to functional outcome. Archives of physical medicine and rehabilitation, 79(10), 1255–1257.

XLIV. Manske, R. C., Lehecka, B. J., Reiman, M. P., & Loudon, J. K. (2018). Orthopedic Joint Mobilization and Manipulation: An Evidence-Based Approach (First ed.). Human Kinetics.

XLV. Martins, F. L., Carvalho, L. C., Silva, C. C., Brasileiro, J. S., Souza, T. O., & Lindquist, A. R. (2012). Immediate effects of TENS and cryotherapy in the reflex excitability and voluntary activity in hemiparetic subjects: a randomized crossover trial. Revista brasileira de fisioterapia (Sao Carlos (Sao Paulo, Brazil)), 16(4), 337–344.

XLVI. Meier, J. D., Aflalo, T. N., Kastner, S., & Graziano, M. S. (2008). Complex organization of human primary motor cortex: a high-resolution fMRI study. Journal of neurophysiology, 100(4), 1800–1812.

XLVII. Michlovitz, S. L., Smith, W., & Watkins, M. (1988). Ice and high voltage pulsed stimulation in treatment of acute lateral ankle sprains*. The Journal of orthopaedic and sports physical therapy, 9(9), 301–304.

XLVIII. Mulligan, BR: Mobilizations with movement (MWM’S). J Manual Manipulative Ther 1(4):154, 1993.

XLIX. Nilsagård, Y., Denison, E., & Gunnarsson, L. G. (2006). Evaluation of a single session with cooling garment for persons with multiple sclerosis--a randomized trial. Disability and rehabilitation. Assistive technology, 1(4), 225–233.

L. Park SJ, Youn PS. (2017). The immediate effect of wrist joint mobilization with taping on range of motion, grip strength, spasticity in stroke patients. J Kor Phys Ther; 29(4):187–93.

LI. Park SJ, Youn PS. The immediate effect of wrist joint mobilization with taping on range of motion, grip strength, spasticity in stroke patients. J Kor Phys Ther. 2017;29(4):187–93.

LII. Park, D., Cynn, H. S., Yi, C., Choi, W. J., Shim, J. H., & Oh, D. W. (2020). Four-week training involving self-ankle mobilization with movement versus calf muscle stretching in patients with chronic stroke: a randomized controlled study. Topics in stroke rehabilitation, 27(4), 296–304.

LIII. Park, D., Lee, J. H., Kang, T. W., & Cynn, H. S. (2019). Four-week training involving ankle mobilization with movement versus static muscle stretching in patients with chronic stroke: a randomized controlled trial. Topics in stroke rehabilitation, 26(2), 81–86.

LIV. Price, R., Lehmann, J. F., Boswell-Bessette, S., Burleigh, A., & deLateur, B. J. (1993). Influence of cryotherapy on spasticity at the human ankle. Archives of physical medicine and rehabilitation, 74(3), 300–304.

LV. Pt Ms, K. C., Pt Ms, C. L. A., & Pt, B. J. (2017). Therapeutic Exercise: Foundations and Techniques (Therapeudic Exercise: Foundations and Techniques) (7th ed.). F.A. Davis Company.

LVI. Pundik, S., McCabe, J., Skelly, M., Tatsuoka, C., & Daly, J. J. (2019). Association of spasticity and motor dysfunction in chronic stroke. Annals of physical and rehabilitation medicine, 62(6), 397–402.

LVII. References without background

LVIII. Saunders, D. G., Walker, J. R., & Levine, D. (2005). Joint mobilization. The Veterinary clinics of North America. Small animal practice, 35(6), 1287–viii.

LIX. Smedes, F., van der Salm, A., Koel, G., & Oosterveld, F. (2014). Manual mobilization of the wrist: a pilot study in rehabilitation of patients with a chronic hemiplegic hand post-stroke. Journal of hand therapy: official journal of the American Society of Hand Therapists, 27(3), 209–216.

LX. Svomp, H. E. M. B. O., & Srp, B. K. B. M. (2005). Maitland’s Peripheral Manipulation: Management of Neuromusculoskeletal Disorders - Volume 2 (4th ed.). Butterworth-Heinemann

LXI. Urban, P. P., Wolf, T., Uebele, M., Marx, J. J., Vogt, T., Stoeter, P., … Wissel, J. (2010). Occurence and Clinical Predictors of Spasticity After Ischemic Stroke. Stroke, 41(9), 2016–2020.

LXII. Wall PD, Melzack R. On nature of cutaneous sensory mechanisms. Brain. 1962;85: 331-356

LXIII. Warren, C. G., Lehmann, J. F., & Koblanski, J. N. (1971). Elongation of rat tail tendon: effect of load and temperature. Archives of physical medicine and rehabilitation, 52(10).

LXIV. Youn, P. S., Cho, K. H., & Park, S. J. (2020). Changes in Ankle Range of Motion, Gait Function and Standing Balance in Children with Bilateral Spastic Cerebral Palsy after Ankle Mobilization by Manual Therapy. Children (Basel, Switzerland), 7(9), 142.

LXV. Zemke, J. E., Andersen, J. C., Guion, W. K., McMillan, J., & Joyner, A. B. (1998). Intramuscular temperature responses in the human leg to two forms of cryotherapy: ice massage and ice bag. The Journal of orthopaedic and sports physical therapy, 27(4), 301–307.